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KMID : 0878220080200020164
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Journal of Sasang Constitutional Medicine
2008 Volume.20 No. 2 p.164 ~ p.170
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A Case of Refractory Ascites Due To Hepatocellular Carcinoma Treated with Sasang Constitutional Medicine
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Jung Yee-Hong
Lee Soo-Kyung
Kim Eun-Hee
Eo Wan-Kyu
Seo Young-Kwang
Choi Won-Cheol
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Abstract
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Objectives : This is a case of refractory ascites due to hepatocellular carcinoma treated with Sasang Constitutional Medication. Refractory ascites, which did not respond to diuretics, was improved with Jeoryeongchajeonja-tang.
Methods : We recorded the patient’s abdominal circumference, body weight and urine output daily. We also investigated the TTKG(transtubular potassium gradient) values 3 times during the treatment course.
Results : the TTKG value of the patient was siginificantly decreased. TTKG values before administration of Jeotyeongchajeonja-tang were 8.41, 10.82, respectively and 4.25 after administration of Jeotyeongchajeonja-tang.
Conclusions : We guess that Jeoryeongchajeonja-tang functions as an aldosterone antagonist or increases spironolactone activity through interaction between Jeotyeongchajeonja-tang and spironolactone. But the mechanism of Jeotyeongchajeonja-tang is not clear, so we need more clinical study of refractory ascites improved with Jeotyeongchajeonja-tang and biological study of interaction between Jeotyeongchajeonja-tang and spironolactone.
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KEYWORD
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Ascites, Hepatocellular Carcinoma, Jeoryeongchajeonja-tang
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